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Alpha-synuclein deposition within sympathetic noradrenergic neurons is associated with myocardial noradrenergic deficiency in neurogenic orthostatic hypotension

Lewy body diseases involve neurogenic orthostatic hypotension (nOH), cardiac noradrenergic deficiency, and deposition of the protein alpha-synuclein (AS) in sympathetic ganglion tissue. Mechanisms linking these abnormalities are poorly understood. One link may be AS deposition within sympathetic neu...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Isonaka, Risa, Rosenberg, Avi Z., Sullivan, Patti, Corrales, Abraham, Holmes, Courtney, Sharabi, Yehonatan, Goldstein, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472912/
https://ncbi.nlm.nih.gov/pubmed/30798661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12642
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