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Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors
Adoptive T cell therapy (ACT) has been established as an efficacious methodology for the treatment of cancer. Identifying targets to enhance the antigen recognition, functional capacity, and longevity of T cells has the potential to broaden the applicability of these approaches in the clinic. We pre...
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| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777814/ https://ncbi.nlm.nih.gov/pubmed/31335326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127847 |
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