A carregar...
The tyrosine phosphatase Ptpn22 discriminates weak, self-peptide from strong agonist T cell receptor signals
T cells must be tolerant of self-antigens to avoid autoimmunity, but responsive to foreign-antigens to provide protection against infection. We found that in both naive and effector T cells, the tyrosine phosphatase, Ptpn22 limits T cell receptor signaling by weak agonist and self-antigens, while no...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148831/ https://ncbi.nlm.nih.gov/pubmed/25108421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2958 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|