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Deletion of PTPN22 improves effector and memory CD8(+) T cell responses to tumors
Adoptive T cell therapy (ACT) has been established as an efficacious methodology for the treatment of cancer. Identifying targets to enhance the antigen recognition, functional capacity, and longevity of T cells has the potential to broaden the applicability of these approaches in the clinic. We pre...
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| Publicado en: | JCI Insight |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777814/ https://ncbi.nlm.nih.gov/pubmed/31335326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127847 |
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