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Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies
The synucleinopathies Parkinson’s disease (PD) and Multiple system atrophy (MSA) — characterized by α-synuclein intracytoplasmic inclusions into, respectively, neurons and oligodendrocytes — are associated with impairment of the autophagy-lysosomal pathways (ALP). Increased expression of the master...
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| 出版年: | JCI Insight |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777809/ https://ncbi.nlm.nih.gov/pubmed/31434803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129719 |
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