Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies

The synucleinopathies Parkinson’s disease (PD) and Multiple system atrophy (MSA) — characterized by α-synuclein intracytoplasmic inclusions into, respectively, neurons and oligodendrocytes — are associated with impairment of the autophagy-lysosomal pathways (ALP). Increased expression of the master...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Arotcarena, Marie-Laure, Bourdenx, Mathieu, Dutheil, Nathalie, Thiolat, Marie-Laure, Doudnikoff, Evelyne, Dovero, Sandra, Ballabio, Andrea, Fernagut, Pierre-Olivier, Meissner, Wassilios G., Bezard, Erwan, Dehay, Benjamin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777809/
https://ncbi.nlm.nih.gov/pubmed/31434803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129719
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