Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown. Here we study the nanoscale organization of pathological ECS in adult...

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Publicado en:Nat Commun
Main Authors: Soria, Federico N., Paviolo, Chiara, Doudnikoff, Evelyne, Arotcarena, Marie-Laure, Lee, Antony, Danné, Noémie, Mandal, Amit Kumar, Gosset, Philippe, Dehay, Benjamin, Groc, Laurent, Cognet, Laurent, Bezard, Erwan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351768/
https://ncbi.nlm.nih.gov/pubmed/32651387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17328-9
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