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Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains unknown. Here we study the nanoscale organization of pathological ECS in adult...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Soria, Federico N., Paviolo, Chiara, Doudnikoff, Evelyne, Arotcarena, Marie-Laure, Lee, Antony, Danné, Noémie, Mandal, Amit Kumar, Gosset, Philippe, Dehay, Benjamin, Groc, Laurent, Cognet, Laurent, Bezard, Erwan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351768/
https://ncbi.nlm.nih.gov/pubmed/32651387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17328-9
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