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Feedback loops in the Plk4–STIL–HsSAS6 network coordinate site selection for procentriole formation

Centrioles are duplicated once in every cell cycle, ensuring the bipolarity of the mitotic spindle. How the core components cooperate to achieve high fidelity in centriole duplication remains poorly understood. By live-cell imaging of endogenously tagged proteins in human cells throughout the entire...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Takao, Daisuke, Watanabe, Koki, Kuroki, Kanako, Kitagawa, Daiju
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777370/
https://ncbi.nlm.nih.gov/pubmed/31533936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.047175
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