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Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells
SAS-6 proteins are thought to impart the ninefold symmetry of centrioles, but the mechanisms by which their assembly occurs within cells remain elusive. In this paper, we provide evidence that the N-terminal, coiled-coil, and C-terminal domains of HsSAS-6 are each required for procentriole formation...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3941056/ https://ncbi.nlm.nih.gov/pubmed/24590172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307049 |
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