Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells

SAS-6 proteins are thought to impart the ninefold symmetry of centrioles, but the mechanisms by which their assembly occurs within cells remain elusive. In this paper, we provide evidence that the N-terminal, coiled-coil, and C-terminal domains of HsSAS-6 are each required for procentriole formation...

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Главные авторы: Keller, Debora, Orpinell, Meritxell, Olivier, Nicolas, Wachsmuth, Malte, Mahen, Robert, Wyss, Romain, Hachet, Virginie, Ellenberg, Jan, Manley, Suliana, Gönczy, Pierre
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941056/
https://ncbi.nlm.nih.gov/pubmed/24590172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307049
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