Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole

Formation of one procentriole next to each pre-existing centriole is essential for centrosome duplication, robust bipolar spindle assembly and maintenance of genome integrity. However, the mechanisms maintaining strict control over centriole copy number are incompletely understood. Here we show that...

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Publicat a:Nat Commun
Autors principals: Ohta, Midori, Ashikawa, Tomoko, Nozaki, Yuka, Kozuka-Hata, Hiroko, Goto, Hidemasa, Inagaki, Masaki, Oyama, Masaaki, Kitagawa, Daiju
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220463/
https://ncbi.nlm.nih.gov/pubmed/25342035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6267
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