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Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole

Formation of one procentriole next to each pre-existing centriole is essential for centrosome duplication, robust bipolar spindle assembly and maintenance of genome integrity. However, the mechanisms maintaining strict control over centriole copy number are incompletely understood. Here we show that...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ohta, Midori, Ashikawa, Tomoko, Nozaki, Yuka, Kozuka-Hata, Hiroko, Goto, Hidemasa, Inagaki, Masaki, Oyama, Masaaki, Kitagawa, Daiju
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220463/
https://ncbi.nlm.nih.gov/pubmed/25342035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6267
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