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Centriole reduplication during prolonged interphase requires procentriole maturation governed by Plk1: Plk1 in procentriole maturation
Supernumerary centrioles lead to abnormal mitosis [1,2] which in turn promotes tumorigenesis [3,4]. Thus, centriole duplication must be coordinated with the cell cycle to ensure that the number of centrioles in the cell doubles precisely during each cell cycle [5]. However, in some transformed cells...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911792/ https://ncbi.nlm.nih.gov/pubmed/20656208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.05.050 |
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