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H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly
The methylation of histone H3 at lysine 9 (H3K9me), performed by the methyltransferase Clr4/SUV39H, is a key event in heterochromatin assembly. In fission yeast, Clr4, together with the ubiquitin E3 ligase Cul4, forms the Clr4 methyltransferase complex (CLRC), whose physiological targets and biologi...
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| Veröffentlicht in: | EMBO Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6776926/ https://ncbi.nlm.nih.gov/pubmed/31468675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948111 |
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