H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly

The methylation of histone H3 at lysine 9 (H3K9me), performed by the methyltransferase Clr4/SUV39H, is a key event in heterochromatin assembly. In fission yeast, Clr4, together with the ubiquitin E3 ligase Cul4, forms the Clr4 methyltransferase complex (CLRC), whose physiological targets and biologi...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Oya, Eriko, Nakagawa, Reiko, Yoshimura, Yuriko, Tanaka, Mayo, Nishibuchi, Gohei, Machida, Shinichi, Shirai, Atsuko, Ekwall, Karl, Kurumizaka, Hitoshi, Tagami, Hideaki, Nakayama, Jun‐ichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776926/
https://ncbi.nlm.nih.gov/pubmed/31468675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948111
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