ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing

Modulation of energy metabolism to a highly glycolytic phenotype, i.e. Warburg effect, is a common phenotype of cancer and activated immune cells allowing increased biomass-production for proliferation and cell division. Endoplasmic reticulum (ER)-localized ADP-dependent glucokinase (ADPGK) has been...

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Publicado no:Sci Rep
Main Authors: Imle, Roland, Wang, Bei-Tzu, Stützenberger, Nicolas, Birkenhagen, Jana, Tandon, Amol, Carl, Matthias, Himmelreich, Nastassja, Thiel, Christian, Gröne, Hermann-Josef, Poschet, Gernot, Völkers, Mirko, Gülow, Karsten, Schröder, Anne, Carillo, Sara, Mittermayr, Stefan, Bones, Jonathan, Kamiński, Marcin Mikołaj, Kölker, Stefan, Sauer, Sven Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776650/
https://ncbi.nlm.nih.gov/pubmed/31582762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50566-6
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