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Structural basis for ADP-dependent glucokinase inhibition by 8-bromo–substituted adenosine nucleotide
In higher eukaryotes, several ATP-utilizing enzymes known as hexokinases activate glucose in the glycolysis pathway by phosphorylation to glucose 6-phosphate. In contrast to canonical hexokinases, which use ATP, ADP-dependent glucokinase (ADPGK) catalyzes noncanonical phosphorylation of glucose to g...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6052215/ https://ncbi.nlm.nih.gov/pubmed/29784881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001562 |
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