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Crystal structure of ADP‐dependent glucokinase from Methanocaldococcus jannaschii in complex with 5‐iodotubercidin reveals phosphoryl transfer mechanism

ADP‐dependent glucokinase (ADPGK) is an alternative novel glucose phosphorylating enzyme in a modified glycolysis pathway of hyperthermophilic Archaea. In contrast to classical ATP‐dependent hexokinases, ADPGK utilizes ADP as a phosphoryl group donor. Here, we present a crystal structure of archaeal...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Tokarz, Piotr, Wiśniewska, Magdalena, Kamiński, Marcin M., Dubin, Grzegorz, Grudnik, Przemysław
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818746/
https://ncbi.nlm.nih.gov/pubmed/29352744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3377
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