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ADP-dependent glucokinase as a novel onco-target for haematological malignancies

Warburg effect or aerobic glycolysis provides selective growth advantage to aggressive cancers. However, targeting oncogenic regulators of Warburg effect has always been challenging owing to the wide spectrum of roles of these molecules in multitude of cells. In this study, we present ADP-dependent...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tandon, Amol, Birkenhagen, Jana, Nagalla, Deepthi, Kölker, Stefan, Sauer, Sven Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423609/
https://ncbi.nlm.nih.gov/pubmed/32788680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70014-0
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