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Epigenetic Suppression of Interferon Lambda Receptor Expression Leads to Enhanced Human Norovirus Replication In Vitro

Human norovirus (HuNoV) is the main cause of gastroenteritis worldwide, yet no therapeutics are currently available. Here, we utilize a human norovirus replicon in human gastric tumor (HGT) cells to identify host factors involved in promoting or inhibiting HuNoV replication. We observed that an inte...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Arthur, Sabastine E., Sorgeloos, Frédéric, Hosmillo, Myra, Goodfellow, Ian G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775457/
https://ncbi.nlm.nih.gov/pubmed/31575769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02155-19
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