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Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling

Excessive bone resorption plays a central role in the development of inflammatory bone diseases, including osteoporosis and rheumatoid arthritis. Thus, identification of agents that can effectively suppress excessive osteoclast formation and function is crucial for the prevention and treatment of in...

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Bibliografische gegevens
Gepubliceerd in:Int J Biol Sci
Hoofdauteurs: Kwak, Sung Chul, Baek, Jong Min, Lee, Chang Hoon, Yoon, Kwon-Ha, Lee, Myeung Su, Kim, Ju-Young
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775311/
https://ncbi.nlm.nih.gov/pubmed/31595160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.28609
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