Acquisition of a side population fraction augments malignant phenotype in ovarian cancer

Side population (SP) cells harbor malignant phenotypes in cancer. The aim of this study was to identify genes that modulate the proportion of ovarian cancer SP cells. Using a shRNA library targeting 15,000 genes, a functional genomics screen was performed to identify genes whose suppression increase...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamanoi, Koji, Baba, Tsukasa, Abiko, Kaoru, Hamanishi, Junzo, Yamaguchi, Ken, Murakami, Ryusuke, Taki, Mana, Hosoe, Yuko, Murphy, Susan K., Konishi, Ikuo, Mandai, Masaki, Matsumura, Noriomi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775117/
https://ncbi.nlm.nih.gov/pubmed/31578411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50794-w
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