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PD-1/PD-L1 blockade in cancer treatment: perspectives and issues

Recent studies showed that tumor cells ‘edit’ host immunity in several ways to evade immune defenses in the tumor microenvironment. This phenomenon is called “cancer immune escape.” One of the most important components in this system is an immunosuppressive co-signal (immune checkpoint) mediated by...

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Bibliografske podrobnosti
izdano v:Int J Clin Oncol
Main Authors: Hamanishi, Junzo, Mandai, Masaki, Matsumura, Noriomi, Abiko, Kaoru, Baba, Tsukasa, Konishi, Ikuo
Format: Artigo
Jezik:Inglês
Izdano: Springer Japan 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901122/
https://ncbi.nlm.nih.gov/pubmed/26899259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10147-016-0959-z
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