Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

Snail is a major transcriptional factor that induces epithelial-mesenchymal transition (EMT). In this study, we explore the effect of Snail on tumor immunity. Snail knockdown in mouse ovarian cancer cells suppresses tumor growth in immunocompetent mice, associated with an increase of CD8(+) tumor-in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Taki, Mana, Abiko, Kaoru, Baba, Tsukasa, Hamanishi, Junzo, Yamaguchi, Ken, Murakami, Ryusuke, Yamanoi, Koji, Horikawa, Naoki, Hosoe, Yuko, Nakamura, Eijiro, Sugiyama, Aiko, Mandai, Masaki, Konishi, Ikuo, Matsumura, Noriomi
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923228/
https://ncbi.nlm.nih.gov/pubmed/29703902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03966-7
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