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HILPDA regulates lipid metabolism, lipid droplet abundance, and response to microenvironmental stress in solid tumors.

Accumulation of lipid droplets has been observed in an increasing range of tumors. However, the molecular determinants of this phenotype and the impact of the tumor microenvironment on lipid droplet dynamics are not well defined. The hypoxia-inducible and lipid droplet associated protein HILPDA is k...

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Podrobná bibliografie
Vydáno v:Mol Cancer Res
Hlavní autoři: VandeKopple, Matthew J., Wu, Jinghai, Auer, Erich N., Giaccia, Amato J., Denko, Nicholas C., Papandreou, Ioanna
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774878/
https://ncbi.nlm.nih.gov/pubmed/31308147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1343
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