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HILPDA regulates lipid metabolism, lipid droplet abundance, and response to microenvironmental stress in solid tumors.

Accumulation of lipid droplets has been observed in an increasing range of tumors. However, the molecular determinants of this phenotype and the impact of the tumor microenvironment on lipid droplet dynamics are not well defined. The hypoxia-inducible and lipid droplet associated protein HILPDA is k...

詳細記述

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書誌詳細
出版年:Mol Cancer Res
主要な著者: VandeKopple, Matthew J., Wu, Jinghai, Auer, Erich N., Giaccia, Amato J., Denko, Nicholas C., Papandreou, Ioanna
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774878/
https://ncbi.nlm.nih.gov/pubmed/31308147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-1343
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