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Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism
Tumor hypoxia reduces the effectiveness of radiation therapy by limiting the biologically effective dose. An acute increase in tumor oxygenation before radiation treatment should therefore significantly improve the tumor cell kill after radiation. Efforts to increase oxygen delivery to the tumor hav...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196495/ https://ncbi.nlm.nih.gov/pubmed/30201710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808945115 |
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