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High-affinity anti-glycan antibodies: challenges and strategies

High-affinity binding of antibodies provides for increased specificity and usually higher effector functions in vivo. This goal, well documented in cancer immunotherapy, is very relevant to vaccines as well, and has particularly significant application toward glycan antigens. The inability to elicit...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Polonskaya, Zinaida, Savage, Paul B., Finn, M.G., Teyton, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774850/
https://ncbi.nlm.nih.gov/pubmed/31029911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.03.004
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