Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies

Use of nicotine-specific monoclonal antibodies (mAbs) to sequester and reduce nicotine distribution to brain has been proposed as a therapeutic approach to treat nicotine addiction (the basis of tobacco use disorder). A series of monoclonal antibodies with high affinity for nicotine (nic•mAbs) was i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raleigh, Michael D., Beltraminelli, Nicola, Fallot, Stephanie, LeSage, Mark G., Saykao, Amy, Pentel, Paul R., Fuller, Steve, Thisted, Thomas, Biesova, Zuzanna, Horrigan, Stephen, Sampey, Darryl, Zhou, Bin, Kalnik, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323890/
https://ncbi.nlm.nih.gov/pubmed/34329335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0254247
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