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Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats

Vaccination against nicotine is under investigation as a treatment for tobacco dependence. Passive immunization with nicotine-specific antibodies represents a complementary strategy to vaccination. A potential adverse effect of passive immunization in nicotine-dependent individuals is that it may le...

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Bibliografiske detaljer
Main Authors: Roiko, Samuel A., Harris, Andrew C., LeSage, Mark G., Keyler, Daniel E., Pentel, Paul R.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709960/
https://ncbi.nlm.nih.gov/pubmed/19393688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2009.04.011
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