Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction

BACKGROUND: Smoking and tobacco use continue to be the largest preventable causes of death globally. A novel therapeutic approach has recently been proposed: administration of an enzyme that degrades nicotine, the main addictive component of tobacco, minimizing brain exposure and reducing its reinfo...

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Détails bibliographiques
Publié dans:BMC Biotechnol
Auteurs principaux: Thisted, Thomas, Biesova, Zuzana, Walmacq, Celine, Stone, Everett, Rodnick-Smith, Max, Ahmed, Shaheda S., Horrigan, Stephen K., Van Engelen, Bo, Reed, Charles, Kalnik, Matthew W.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6679477/
https://ncbi.nlm.nih.gov/pubmed/31375100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0551-5
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