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Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease
Filament formation by enzymes is increasingly recognized as an important phenomenon with potentially unique regulatory properties and biological roles. SgrAI is an allosterically regulated type II restriction endonuclease that forms filaments with enhanced DNA cleavage activity and altered sequence...
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| 出版年: | Structure |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6774820/ https://ncbi.nlm.nih.gov/pubmed/31447289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.08.001 |
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