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Activation of DNA Cleavage by Oligomerization of DNA Bound SgrAI

SgrAI is a type II restriction endonuclease that cuts an unusually long recognition sequence and exhibits allosteric self-modulation of DNA activity and sequence specificity. Precleaved primary site DNA has been shown to be an allosteric effector [Hingorani-Varma & Bitinaite, (2003) J. Biol. Che...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Chad K., Stiteler, Amanda P., Shah, Santosh, Ghare, M. Imran, Bitinaite, Jurate, Horton, Nancy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972665/
https://ncbi.nlm.nih.gov/pubmed/20836535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100557v
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