The bHLH Gene Hes1 as a Repressor of the Neuronal Commitment of CNS Stem Cells

Hes1 is one of the basic helix-loop-helix transcription factors that regulate mammalian CNS development, and its loss- and gain-of-function phenotypes indicate that it negatively regulates neuronal differentiation. Here we report that Hes1(−/−) mice expressed both early (TuJ1 and Hu) and late (MAP2...

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Udgivet i:J Neurosci
Main Authors: Nakamura, Yuki, Sakakibara, Shin-ichi, Miyata, Takaki, Ogawa, Masaharu, Shimazaki, Takuya, Weiss, Samuel, Kageyama, Ryoichiro, Okano, Hideyuki
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774123/
https://ncbi.nlm.nih.gov/pubmed/10627606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-01-00283.2000
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