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Real-time imaging of bHLH transcription factors reveals their dynamic control in the multipotency and fate choice of neural stem cells
The basic-helix-loop-helix (bHLH) transcription factors Ascl1/Mash1, Hes1, and Olig2 regulate the fate choice of neurons, astrocytes, and oligodendrocytes, respectively; however, these factors are coexpressed in self-renewing multipotent neural stem cells (NSCs) even before cell fate determination....
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Publicado no: | Front Cell Neurosci |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4523821/ https://ncbi.nlm.nih.gov/pubmed/26300726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00288 |
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