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The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
Transient receptor potential melastatin channel subfamily member 2 (TRPM2) has an essential role in protecting cell viability through modulation of oxidative stress. TRPM2 is highly expressed in cancer. When TRPM2 is inhibited, mitochondria are dysfunctional, ROS levels are increased, and cell viabi...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773863/ https://ncbi.nlm.nih.gov/pubmed/31575956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50661-8 |
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