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Illuminating G-Protein-Coupling Selectivity of GPCRs
Heterotrimetic G proteins consist of four subfamilies (G(S), G(i/O), G(q/11), and G(12/13)) that mediate signaling via G-protein-coupled receptors (GPCRs), principally by receptors binding Gα C termini. G-protein-coupling profiles govern GPCR-induced cellular responses, yet receptor sequence selecti...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773469/ https://ncbi.nlm.nih.gov/pubmed/31160049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.04.044 |
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