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JAK3 inhibitor-based immunosuppression in allogeneic islet transplantation in cynomolgus monkeys
Islet transplantation is efficacious to prevent severe hypoglycemia and glycemic liability of selected patients of type 1 diabetes. However, since calcineurin inhibitor (CNI) causes β-cell and nephrotoxicity, alternative drug(s) with similar potency and safety profile to CNI will be highly desirable...
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| Publicado no: | Islets |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6773385/ https://ncbi.nlm.nih.gov/pubmed/31483188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2019.1650580 |
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