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Pre-clinical results in pig-to-nonhuman primate islet xenotransplantation using anti-CD40 antibody (2C10R4)-based immunosuppression

BACKGROUND: Islet transplantation is an effective therapy for selected patients with type 1 diabetes with labile glycemic control and hypoglycemic unawareness, but donor organs are limited. Islet xenotransplantation using porcine islets will potentially solve this problem. Although successful proof...

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Detalhes bibliográficos
Publicado no:Xenotransplantation
Main Authors: Shin, Jun-Seop, Kim, Jong-Min, Min, Byoung-Hoon, Yoon, Il Hee, Kim, Hyun Je, Kim, Jung-Sik, Kim, Yong-Hee, Kang, Seong-Jun, Kim, Jiyeon, Kang, Hee-Jung, Lim, Dong-Gyun, Hwang, Eung-Soo, Ha, Jongwon, Kim, Sang-Joon, Park, Wan Beom, Park, Chung-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809197/
https://ncbi.nlm.nih.gov/pubmed/29057561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12356
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