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Prolonged Survival of Allogeneic Islets in Cynomolgus Monkeys After Short-Term Triple Therapy

Preclinical studies in nonhuman primates (NHP) are particularly useful to evaluate the safety and efficacy of new therapeutic proteins developed for use in clinical transplantation. We hypothesized that a treatment that selectively destroys activated cytopathic donor reactive T cells while sparing r...

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Main Authors: Koulmanda, M., Qipo, A., Fan, Z., Smith, N., Auchincloss, H., Zheng, X. X., Strom, T. B.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743408/
https://ncbi.nlm.nih.gov/pubmed/22390179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.03973.x
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