High cGMP and low PDE3A activity are associated with oocyte meiotic incompetence

Resumption of meiosis in mammalian oocytes, defined as oocyte maturation, is stimulated by luteinizing hormone (LH). Fully grown oocytes can also mature spontaneously, upon their release from the ovarian follicle. However, growing oocytes fail to resume meiosis in vitro and the mechanism underlying...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Gershon, Eran, Maimon, Iris, Galiani, Dalia, Elbaz, Michal, Karasenti, Sharon, Dekel, Nava
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773239/
https://ncbi.nlm.nih.gov/pubmed/31401933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1652472
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