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High cGMP and low PDE3A activity are associated with oocyte meiotic incompetence

Resumption of meiosis in mammalian oocytes, defined as oocyte maturation, is stimulated by luteinizing hormone (LH). Fully grown oocytes can also mature spontaneously, upon their release from the ovarian follicle. However, growing oocytes fail to resume meiosis in vitro and the mechanism underlying...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Gershon, Eran, Maimon, Iris, Galiani, Dalia, Elbaz, Michal, Karasenti, Sharon, Dekel, Nava
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773239/
https://ncbi.nlm.nih.gov/pubmed/31401933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1652472
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