Intracellular ATP Increases Capsaicin-Activated Channel Activity by Interacting with Nucleotide-Binding Domains

Capsaicin (CAP)-activated ion channel plays a key role in generating nociceptive neural signals in sensory neurons. Here we present evidence that intracellular ATP upregulates the activity of capsaicin receptor channel. In inside-out membrane patches isolated from sensory neurons, application of CAP...

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Publicado en:J Neurosci
Main Authors: Kwak, Jiyeon, Wang, Myeong Hyeon, Hwang, Sun Wook, Kim, Tae-Yoon, Lee, Soon-Youl, Oh, Uhtaek
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2000
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ARTICLE
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773187/
https://ncbi.nlm.nih.gov/pubmed/11069936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-22-08298.2000
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