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Neuroactive Steroid 3α-Hydroxy-5α-Pregnan-20-One Modulates Electrophysiological and Behavioral Actions of Ethanol

Neuroactive steroids are synthesized de novo in brain, yet their physiological significance remains elusive. We provide biochemical, electrophysiological, and behavioral evidence that several specific actions of alcohol (ethanol) are mediated by the neurosteroid 3α-hydroxy-5α-pregnan-20-one (3α,5α-T...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: VanDoren, Margaret J., Matthews, Douglas B., Janis, Gregory C., Grobin, A. Chistina, Devaud, Leslie L., Morrow, A. Leslie
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2000
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772919/
https://ncbi.nlm.nih.gov/pubmed/10684899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-05-01982.2000
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