Neuroactive Steroid 3α-Hydroxy-5α-Pregnan-20-One Modulates Electrophysiological and Behavioral Actions of Ethanol

Neuroactive steroids are synthesized de novo in brain, yet their physiological significance remains elusive. We provide biochemical, electrophysiological, and behavioral evidence that several specific actions of alcohol (ethanol) are mediated by the neurosteroid 3α-hydroxy-5α-pregnan-20-one (3α,5α-T...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: VanDoren, Margaret J., Matthews, Douglas B., Janis, Gregory C., Grobin, A. Chistina, Devaud, Leslie L., Morrow, A. Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772919/
https://ncbi.nlm.nih.gov/pubmed/10684899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-05-01982.2000
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