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Pregnenolone Sulfate Modulates Inhibitory Synaptic Transmission by Enhancing GABA(A) Receptor Desensitization
We examined the effects of the neurosteroid pregnenolone sulfate (PS) on GABA(A) receptor-mediated synaptic currents and currents elicited by rapid applications of GABA onto nucleated outside-out patches in cultured postnatal rat hippocampal neurons. At 10 μm, PS significantly depressed peak respons...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2000
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772674/ https://ncbi.nlm.nih.gov/pubmed/10804198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-10-03571.2000 |
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