Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

Positive modulators of NMDA receptors are important candidates for therapeutic development to treat psychiatric disorders including autism and schizophrenia. Sulfated neurosteroids have been studied as positive allosteric modulators of NMDA receptors for years, but we understand little about the cel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropharmacology
Prif Awduron: Chisari, Mariangela, Wilding, Timothy J., Brunwasser, Samuel, Krishnan, Kathiresan, Qian, Mingxing, Benz, Ann, Huettner, James E., Zorumski, Charles F., Covey, Douglas F., Mennerick, Steven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286210/
https://ncbi.nlm.nih.gov/pubmed/30332607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.10.015
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