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Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization

Positive modulators of NMDA receptors are important candidates for therapeutic development to treat psychiatric disorders including autism and schizophrenia. Sulfated neurosteroids have been studied as positive allosteric modulators of NMDA receptors for years, but we understand little about the cel...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Chisari, Mariangela, Wilding, Timothy J., Brunwasser, Samuel, Krishnan, Kathiresan, Qian, Mingxing, Benz, Ann, Huettner, James E., Zorumski, Charles F., Covey, Douglas F., Mennerick, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286210/
https://ncbi.nlm.nih.gov/pubmed/30332607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.10.015
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