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Dysfunctions in Mice by NMDA Receptor Point Mutations NR1(N598Q) and NR1(N598R)

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutatedNR1 alleles, NR1(Q/Q) andNR1(−/R) mice, developed a perinatally lethal phenotype mainly characterized by r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neurosci
मुख्य लेखकों: Single, Frank N., Rozov, Andrei, Burnashev, Nail, Zimmermann, Frank, Hanley, Daniel F., Forrest, Douglas, Curran, Tom, Jensen, Vidar, Hvalby, Øivind, Sprengel, Rolf, Seeburg, Peter H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772252/
https://ncbi.nlm.nih.gov/pubmed/10729336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-07-02558.2000
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