Dissecting Spatial Knowledge from Spatial Choice by Hippocampal NMDA Receptor Deletion

Hippocampal NMDA receptors (NMDARs) and NMDAR-dependent synaptic plasticity are widely considered as crucial substrates of long-term spatial memory, although their precise role remains uncertain. Here we show that GluN1(ΔDGCA1) mice, lacking NMDARs in all dentate gyrus and dorsal CA1 principal cells...

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Detalhes bibliográficos
Main Authors: Bannerman, David M., Bus, Thorsten, Taylor, Amy, Sanderson, David J., Schwarz, Inna, Jensen, Vidar, Hvalby, Øivind, Rawlins, J. Nicholas P., Seeburg, Peter H., Sprengel, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442238/
https://ncbi.nlm.nih.gov/pubmed/22797694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3166
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