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Dysfunctions in Mice by NMDA Receptor Point Mutations NR1(N598Q) and NR1(N598R)
NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutatedNR1 alleles, NR1(Q/Q) andNR1(−/R) mice, developed a perinatally lethal phenotype mainly characterized by r...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772252/ https://ncbi.nlm.nih.gov/pubmed/10729336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-07-02558.2000 |
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