Dysfunctions in Mice by NMDA Receptor Point Mutations NR1(N598Q) and NR1(N598R)

NMDA receptors in mice were mutated by gene targeting to substitute asparagine (N) in position 598 of the NR1 subunit to glutamine (Q) or arginine (R). Animals expressing exclusively the mutatedNR1 alleles, NR1(Q/Q) andNR1(−/R) mice, developed a perinatally lethal phenotype mainly characterized by r...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Single, Frank N., Rozov, Andrei, Burnashev, Nail, Zimmermann, Frank, Hanley, Daniel F., Forrest, Douglas, Curran, Tom, Jensen, Vidar, Hvalby, Øivind, Sprengel, Rolf, Seeburg, Peter H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2000
Onderwerpen:
ARTICLE
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772252/
https://ncbi.nlm.nih.gov/pubmed/10729336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-07-02558.2000
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items