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Impaired Long-Term Memory and NR2A-Type NMDA Receptor-Dependent Synaptic Plasticity in Mice Lacking c-Fos in the CNS

The immediate early gene c-fos is part of the activator protein-1 transcription factor and has been postulated to participate in the molecular mechanisms of learning and memory. To test this hypothesis in vivo, we generated mice with a nervous system-specific c-fos knock-out using the Cre-loxP syste...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Fleischmann, Alexander, Hvalby, Oivind, Jensen, Vidar, Strekalova, Tatyana, Zacher, Christiane, Layer, Liliana E., Kvello, Ane, Reschke, Markus, Spanagel, Rainer, Sprengel, Rolf, Wagner, Erwin F., Gass, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740829/
https://ncbi.nlm.nih.gov/pubmed/14534245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-27-09116.2003
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