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KIT mutation in a naïve succinate dehydrogenase‐deficient gastric GIST

Up to 85% of gastrointestinal stromal tumors (GIST) harbor mutually exclusive mutations in the KIT or the PDGFRA gene. Among others, known as wild type GIST, succinate dehydrogenase (SDH)‐deficient tumors develop due to genetic or epigenetic alterations in any of four SDH genes. Herein, we present a...

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Detalhes bibliográficos
Publicado no:Genes Chromosomes Cancer
Main Authors: Brcic, Iva, Kashofer, Karl, Skone, Daniela, Liegl‐Atzwanger, Bernadette
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771634/
https://ncbi.nlm.nih.gov/pubmed/31124195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22768
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