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SUCCINATE DEHYDROGENASE DEFICIENT GISTS – A CLINICOPATHOLOGIC, IMMUNOHISTOCHEMICAL, AND MOLECULAR GENETIC STUDY OF 66 GASTRIC GISTS WITH PREDILECTION TO YOUNG AGE
Most gastrointestinal stromal tumors (GISTs) are driven by KIT or PDGFRA activating mutations, but a small subset is associated with loss function of the succinate dehydrogenase (SDH) complex of mitochondrial inner membrane proteins. This occurs via germline mutations of the SDH subunit genes and hi...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193596/ https://ncbi.nlm.nih.gov/pubmed/21997692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3182260752 |
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