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Significance of KIT and PDGFRA mutations in gastric gist imatinib - naive surgically treated patients

Background/Aim. KIT (KIT proto-oncogene receptor tyrosine kinase) and PDGFRA (platelet-derived growth factor receptor alpha) gene mutations represent major molecular forces inside the gastrointestinal stromal tumors (GIST). Aim of this study was to evaluate these mutations in the patients who underw...

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Principais autores: Ebrahimi Keramatollah, Sabljak Predrag, Simić Aleksandar, Skrobić Ognjan, Veličković Dejan, Šljukić Vladimir, Novaković Ivana, Dobričić Valerija, Micev Marjan, Peško Predrag
Format: Artigo
Sprog:Inglês
Udgivet: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2019-01-01
Serier:Vojnosanitetski Pregled
Fag:
gastrointestinal stromal tumors
genes
mutation
digestive system surgical procedures
neoplasm metastasis
prognosis
survival
Online adgang:http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501800048E.pdf
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